Article

Myeloid CCN3 protects against aortic valve calcification

2022-11-03

Abstract excerpt

<h4>Background: </h4> Cellular communication network factor 3 (CCN3) has been implicated in the regulation of osteoblast differentiation. However, it is not known if CCN3 can regulate valvular calcification. While macrophages have been shown to regulate valvular calcification, the molecular and cellular mechanisms of this process remain poorly understood. In the present study, we investigated the role of macrophag...

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Literature Corpus work: b8946fc6-354a-5961-9cbe-175ccb4379d3
DOI: 10.21203/rs.3.rs-2224373/v1

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