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Notch Signaling in Cardiovascular Disease and Calcification

1 Aug 2008

Abstract excerpt

Recent increase in human lifespan has shifted the spectrum of aging-related disorders to an unprecedented upsurge in cardiovascular diseases, especially calcific aortic valve stenosis, which has an 80% risk of progression to heart failure and death. A current therapeutic option for calcified valves is surgical replacement, which provides only temporary relief. Recent progress in cardiovascular research has...

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PMID: 19936191
DOI: 10.2174/157340308785160552

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