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Article

Microglial Phenotypes and Functions in Multiple Sclerosis.

Cold Spring Harbor perspectives in medicine - 1 Feb 2018

O'Loughlin Elaine, Madore Charlotte, Lassmann Hans, Butovsky Oleg

Abstract excerpt

Microglia are the resident immune cells that constantly survey the central nervous system. They can adapt to their environment and respond to injury or insult by altering their morphology, phenotype, and functions. It has long been debated whether microglial activation is detrimental or beneficial in multiple sclerosis (MS). Recently, the two opposing yet connected roles of microglial activation have been...

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Identifiers

PMID: 29419406
DOI: 10.1101/cshperspect.a028993
PMCID: PMC5793738

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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