Article

Assessment of Metabolic Imaging Biomarkers for MEK Inhibition Therapy Response in Melanoma

2024-06-19

Abstract excerpt

The MAPK signaling pathway with BRAF mutations has been shown to drive the pathogenesis of 40-60% of melanomas. Inhibitors of this pathway's BRAF and MEK components are currently used to treat these malignancies. However, responses to these treatments are not always successful. Therefore, identifying noninvasive biomarkers to predict treatment responses is essential for personalized medicine of melanoma patie...

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Literature Corpus work: b78dfc97-df0f-5b09-b939-fbefb0d1e2cf
DOI: 10.20944/preprints202406.1354.v1

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