Article
Correlation between early 18F-FDG PET/CT response to BRAF and MEK inhibition and survival in patients with BRAF-mutant metastatic melanoma.
Nuclear medicine communications - 1 Feb 2016
Schmitt Ronald J, Kreidler Sarah M, Glueck Deborah H, Amaria Rodabe N, Gonzalez Rene, Lewis Karl, Bagrosky Brian M, Kwak Jennifer J, Koo Phillip J
Abstract excerpt
PURPOSE: Metabolic response to treatment measured by fluorine-18 fluorodeoxyglucose ((18)F-FDG) PET has prognostic implications in many cancers. This study investigated the association between survival and early changes on (18)F-FDG PET/computed tomography (CT) for patients with BRAF-mutant melanoma receiving combined BRAF and MEK inhibition therapy. MATERIALS AND METHODS: Overall, 24 patients with advanced...
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