Article
Magnetic resonance spectroscopic imaging of tumor metabolic markers for cancer diagnosis, metabolic phenotyping, and characterization of tumor microenvironment.
Disease markers - 1 Jan 2000
He Qiuhong, Xu Ray Z, Shkarin Pavel, Pizzorno Giuseppe, Lee-French Carol H, Rothman Douglas L, Shungu Dikoma C, Shim Hyunsuk
Abstract excerpt
Cancer cells display heterogeneous genetic characteristics, depending on the tumor dynamic microenvironment. Abnormal tumor vasculature and poor tissue oxygenation generate a fraction of hypoxic tumor cells that have selective advantages in metastasis and invasion and often resist chemo- and radi...
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