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Article

Ketogenic diets slow melanoma growth in vivo regardless of tumor genetics and metabolic plasticity

18 Jul 2022

Abstract excerpt

BACKGROUND: Growing evidence supports the use of low-carbohydrate/high-fat ketogenic diets as an adjunctive cancer therapy. However, it is unclear which genetic, metabolic, or immunological factors contribute to the beneficial effect of ketogenic diets. Therefore, we investigated the effect of ketogenic diets on the progression and metabolism of genetically and metabolically heterogeneous melanoma xenografts, as...

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PMID: 35851093
DOI: 10.1186/s40170-022-00288-7

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