Article

Genome-wide polygenic risk score method for diabetic kidney disease in patients with type 2 diabetes

2021-07-10

Abstract excerpt

<h4>ABSTRACT</h4> Diabetic kidney disease (DKD) is considered partially hereditary, but the genetic factors underlying disease remain largely unknown. A key barrier to our understanding stems from its heterogeneity, and likely polygenic etiology. Proteinuric and non-proteinuric DKD are two sub-classes of DKD, defined by high urinary albumin-to-creatinine ratio (UACR) and low creatinine estimated glomerular filtrat...

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Literature Corpus work: 00971947-d56c-58a9-a6e8-1c90138b8967
DOI: 10.1101/2021.07.09.21260114

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