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A Micro-scale Humanized Ventilator-on-a-Chip to Examine the Injurious Effects of Mechanical Ventilation

2024-03-01

Abstract excerpt

Patients with compromised respiratory function frequently require mechanical ventilation to survive. Unfortunately, non-uniform ventilation of injured lungs generates complex mechanical forces that lead to ventilator induced lung injury (VILI). Although investigators have developed lung-on-a-chip systems to simulate normal respiration, modeling the complex mechanics of VILI as well as the subsequent recovery phase...

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Literature Corpus work
b7143130-8012-5727-bdb5-ecf5f228140f
DOI
10.1101/2024.02.26.582200
Open publication

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A Micro-scale Humanized Ventilator-on-a-Chip to Examine the Injurious Effects of Mechanical VentilationDOI 10.1101/2024.02.26.582200
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