Article

Organ on chip model of respiratory vascular interactions under COPD relevant oxidative stress

2026-06-09

Abstract excerpt

Oxidative stress-induced airway injury contributes to chronic obstructive pulmonary disease (COPD). Cardiovascular complications increase COPD morbidity and mortality, but mechanistic links between airway injury and vascular dysfunction remain unclear, largely due to limitations of in vitro models that fail to replicate the multicellular lung environment. We developed REVAS, a modular organ-on-chip platform to s...

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Literature Corpus work: a7047488-f35c-5290-81f0-95495521ae22
DOI: 10.64898/2026.06.04.730087

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