Endothelial cell signaling and ventilator-induced lung injury: molecular mechanisms, genomic analyses, and therapeutic targets

Abstract excerpt

Mechanical ventilation is a life-saving intervention in critically ill patients with respiratory failure due to acute respiratory distress syndrome (ARDS). Paradoxically, mechanical ventilation also creates excessive mechanical stress that directly augments lung injury, a syndrome known as ventilator-induced lung injury (VILI). The pathobiology of VILI and ARDS shares many inflammatory features including...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Immune cells in cancer
• Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms
• Share to Respiratory Support and Mechanisms