Extracorporeal Carbon Dioxide Removal in Acute Respiratory Distress Syndrome: Physiologic Rationale and Phenotype-Based Perspectives.

doi:10.3390/medicina62020236

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Extracorporeal Carbon Dioxide Removal in Acute Respiratory Distress Syndrome: Physiologic Rationale and Phenotype-Based Perspectives.

Medicina (Kaunas, Lithuania) - 23 Jan 2026

Merola Raffaele, Battaglini Denise, De Rosa Silvia

Abstract excerpt

Acute respiratory distress syndrome (ARDS) is a major cause of morbidity and mortality despite decades of progress in ventilatory support. Mechanical ventilation, while essential for oxygenation, may exacerbate lung injury through excessive mechanical power delivery, even when using lung-protective strategies. Extracorporeal carbon dioxide removal (ECCO2R) was conceived to enable "ultra-protective" ventilation,...

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PMID: 41752636
DOI: 10.3390/medicina62020236
PMCID: PMC12941739

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