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Article

Reproducible uniform equibiaxial stretch of precision-cut lung slices.

American journal of physiology. Lung cellular and molecular physiology - 15 Feb 2013

Davidovich N, Huang J, Margulies S S

Abstract excerpt

Simulating ventilator-induced lung injury (VILI) in the laboratory requires stretching of lung alveolar tissue. Whereas precision-cut lung slices (PCLSs) are widely used for studying paracrine signaling pathways in the lungs, their use in stretch studies is very limited because of the technical challenge of fixing them to a stretchable substrate, stretching them uniformly, or holding them in a stretch device...

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Identifiers

PMID: 23275624
DOI: 10.1152/ajplung.00224.2012
PMCID: PMC3567360

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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