Article
The effect of the mechanodynamic lung environment on fibroblast phenotype via the Flexcell.
BMC pulmonary medicine - 27 Jul 2024
Al Yazeedi S, Abokor A F, Brussow J, Thiam F, Phogat S, Osei E T
Abstract excerpt
The lung is a highly mechanical organ as it is exposed to approximately 109 strain cycles, (where strain is the length change of tissue structure per unit initial length), with an approximately 4% amplitude change during quiet tidal breathing or 107 strain cycles at a 25% amplitude during heavy exercises, sighs, and deep inspirations. These mechanical indices have been reported to become aberrant in lung diseases...
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