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Breathing on Chip: Dynamic flow and stretch tune cellular composition and accelerate mucociliary maturation of airway epithelium <i>in vitro</i>

2021-05-08

Abstract excerpt

Human lung function is intricately linked to blood flow and breathing cycles, but it remains unknown how these dynamic cues shape human airway epithelial biology. Here we report a state-of-the-art protocol for studying effects of physiological airflow and stretch on differentiation, cellular composition, and mucociliary clearance of human primary airway epithelial cells cultured on a perfused airway chip. Perfused...

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Identifiers and source

Literature Corpus work
00e5ea53-0166-5b35-9195-aaf2e223a813
DOI
10.1101/2021.05.07.443164
Open publication

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Breathing on Chip: Dynamic flow and stretch tune cellular composition and accelerate mucociliary maturation of airway epithelium <i>in vitro</i>DOI 10.1101/2021.05.07.443164
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