Article

Fusion of DARPin to aldolase enables visualization of small protein by cryoEM

2018-10-30

Abstract excerpt

In recent years, solving protein structures by single particle cryogenic electron microscopy (cryoEM) has become a crucial tool in structural biology. While exciting progress is being made towards the visualization of smaller and smaller macromolecules, the median protein size in both eukaryotes and bacteria is still beyond the reach of single particle cryoEM. To overcome this problem, we implemented a platform st...

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Literature Corpus work: b6dab8fb-81cc-5fa3-a002-72a9bb849c9e
DOI: 10.1101/455063

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