Article

Heteromeric amyloid filaments of ANXA11 and TDP-43 in FTLD-TDP Type C

2024-06-26

Abstract excerpt

<h4>SUMMARY</h4> Neurodegenerative diseases are characterised by the abnormal filamentous assembly of specific proteins in the central nervous system 1 . Human genetic studies established a causal role for protein assembly in neurodegeneration 2 . However, the underlying molecular mechanisms remain largely unknown, which is limiting progress in developing clinical tools for these diseases. Recent advances in el...

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Literature Corpus work: 5144e5c2-99f9-5a7f-99ab-6b96ea4f0512
DOI: 10.1101/2024.06.25.600403

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