Article

Structure of phage λ Redβ <sub>177</sub> annealase shows how it anneals DNA strands during single-strand annealing homologous DNA recombination

2022-04-09

Abstract excerpt

The bacteriophage λ red recombination system catalyzes the single-strand annealing homologous DNA recombination reaction, in which Redβ annealase protein plays a critical role. Using cryogenic electron microscopy, we were able to determine a structure of a C-terminally truncated Redβ with the residues 1-177 bound to two complementary 27mer oligonucleotides forming an annealing intermediate, to a final resolution o...

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Literature Corpus work: 62267ec4-4c69-574b-98c8-064b1c56b5ed
DOI: 10.1101/2022.04.09.487726

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