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Rifampicin tolerance and growth fitness among isoniazid-resistant clinical <i>Mycobacterium tuberculosis</i> isolates: an in-vitro longitudinal study

2023-11-22

Abstract excerpt

Antibiotic tolerance in Mycobacterium tuberculosis leads to less effective bacterial killing, poor treatment responses and resistant emergence. Therefore, we investigated the rifampicin tolerance of M. tuberculosis isolates, with or without pre-existing isoniazid-resistance. We determined the in-vitro rifampicin survival fraction by minimum duration of killing assay in isoniazid susceptible (IS, n=119) and resi...

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Literature Corpus work
b68676e5-3bc4-588b-8829-5d81f4c2c37d
DOI
10.1101/2023.11.22.568240
Open publication

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Rifampicin tolerance and growth fitness among isoniazid-resistant clinical <i>Mycobacterium tuberculosis</i> isolates: an in-vitro longitudinal studyDOI 10.1101/2023.11.22.568240
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