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Variability in intrinsic drug tolerance in <i>Mycobacterium tuberculosis</i> corresponds with phylogenetic lineage

2025-07-04

Abstract excerpt

Drug tolerance allows bacteria to survive extended exposure to bactericidal drugs and is thought to play a role in drug resistance evolution. In Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), multidrug resistant TB (MDR-TB) outbreaks are frequently caused by strains belonging to two phylogenetic lineages of the human-adapted strains of the Mtb Complex, namely lineages (L) 2 and L4. We...

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Literature Corpus work
e5a92e97-ef4f-536f-b227-1efa6d6ffb13
DOI
10.1101/2025.07.04.663131
Open publication

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Variability in intrinsic drug tolerance in <i>Mycobacterium tuberculosis</i> corresponds with phylogenetic lineageDOI 10.1101/2025.07.04.663131
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