Article

The Cytoplasmic Ceiling: Golgi-Trafficking Machinery as the Division-Dependent Repository of Cellular Age Information

2026-02-02

Abstract excerpt

<title>Abstract</title> <p>Background Induced pluripotent stem cell (iPSC)-derived neurons undergo complete rejuvenation regardless of donor age, while directly converted induced neurons (iNs) retain transcriptomic and functional aging signatures. Despite extensive investigation over the past decade, no mechanistic explanation has been established for why cell division-rather than transcription factor activity a...

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Literature Corpus work: b6016f09-742b-53d0-b154-8ab25399e2cb
DOI: 10.21203/rs.3.rs-8744483/v1

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