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Expression of Exosome Biogenesis Genes is Pervasively Altered by Aging in the Mouse and in the Human Brain During Alzheimer’s Disease

2021-08-05

Abstract excerpt

Extracellular vesicles (EVs) like exosomes are secreted by numerous cell types in a variety of tissues. EVs have been implicated in both aging and age-related disorders like Alzheimer’s disease (AD). However, how aging and AD affect EV biogenesis within and across cell types is poorly understood. Moreover, cells acquire characteristics based on tissue niche, but the impact of tissue residence on cell type EV bioge...

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Literature Corpus work
73b007d8-6574-5818-a27f-c4f921f31a39
DOI
10.1101/2021.08.02.21260877
Open publication

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Expression of Exosome Biogenesis Genes is Pervasively Altered by Aging in the Mouse and in the Human Brain During Alzheimer’s DiseaseDOI 10.1101/2021.08.02.21260877
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