Article
Expression of Exosome Biogenesis Genes is Pervasively Altered by Aging in the Mouse and in the Human Brain During Alzheimer’s Disease
2021-08-05
Abstract excerpt
Extracellular vesicles (EVs) like exosomes are secreted by numerous cell types in a variety of tissues. EVs have been implicated in both aging and age-related disorders like Alzheimer’s disease (AD). However, how aging and AD affect EV biogenesis within and across cell types is poorly understood. Moreover, cells acquire characteristics based on tissue niche, but the impact of tissue residence on cell type EV bioge...
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Identifiers and source
- Literature Corpus work
- 73b007d8-6574-5818-a27f-c4f921f31a39
- DOI
- 10.1101/2021.08.02.21260877
