Article

Identification of markers for neurescence through transcriptomic profiling of postmortem human brains

2025-04-09

Abstract excerpt

<title>Abstract</title> <p>Neuronal senescence (i.e., neurescent) is an important hallmark of aging and neurodegeneration, but it remains poorly characterized in the human brain due to the lack of reliable markers. This study aimed to identify neurescent markers based on single-nucleus transcriptome data from postmortem human prefrontal cortex. Using an eigengene approach, we integrated three gene panels: a) SenM...

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Literature Corpus work: 2faa5198-4010-5301-afe3-5fb396e110e8
DOI: 10.21203/rs.3.rs-5903682/v1

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