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Human iPSC-Derived Neurons as A Platform for Deciphering the Mechanisms behind Brain Aging

7 Nov 2021

Abstract excerpt

With an increased life expectancy among humans, aging has recently emerged as a major focus in biomedical research. The lack of in vitro aging models-especially for neurological disorders, where access to human brain tissues is limited-has hampered the progress in studies on human brain aging and various age-associated neurodegenerative diseases at the cellular and molecular level. In this review, we provide an...

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PMID: 34829864
DOI: 10.3390/biomedicines9111635

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