Article
Golgi fragmentation - One of the earliest organelle phenotypes in Alzheimer’s disease neurons
2022-12-09
Abstract excerpt
<h4>ABSTRACT</h4> Alzheimer’s disease (AD) is the most common cause of dementia, with no current cure. Consequently, alternative approaches focusing on early pathological events in specific neuronal populations, besides targeting the well-studied Amyloid beta (Aβ) accumulations and Tau tangles, are needed. In this study, we have investigated disease phenotypes specific to glutamatergic forebrain neurons and mappe...
Topics
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- Alzheimer's disease research and treatments
- Autophagy in Disease and Therapy
- Cellular transport and secretion
- Endoplasmic Reticulum Stress and Disease
- Nerve injury and regeneration
- Neurogenesis and neuroplasticity mechanisms
- Neuroscience and Neuropharmacology Research
- Parkinson's Disease Mechanisms and Treatments
Identifiers and source
- Literature Corpus work
- a3a18de2-8197-545e-a3ef-620f5b6855e8
- DOI
- 10.1101/2022.12.09.519571
