Article

Regulation of nuclear receptor Esrrb function by Ncoa3 in mouse embryonic stem cell pluripotency

2013-01-01

Abstract excerpt

The mouse embryonic stem cell (ESC) state depends upon a gene regulatory network centred on Oct4, Sox2 and Nanog (OSN). Notably, these and other key transcription factors (TFs) assemble in large, multi-protein complexes at enhancer loci to drive the high expression of target genes. It remains unclear, however, how each specific TF functions in transcription, and whether each depends on protein-protein interactions...

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Literature Corpus work: b5f1aa7b-8e33-584b-a43c-d6d10dda8fb6
DOI: 10.25560/14683

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