Article
ESRRB plays a crucial role in the promotion of porcine cell reprograming.
Journal of cellular physiology - 1 Feb 2018
Yang Fan, Ren Yahui, Li Huan, Wang Huayan
Abstract excerpt
The estrogen-related receptor b (ESRRB) is an orphan nuclear receptor and targets many genes involved in self-renewal and pluripotency. In mouse ES cells, overexpression of ESRRB can maintain LIF-independent self-renewal in the absence of Nanog. However, the fundamental features of porcine ESRRB remain elusive. In this study, we revealed the expression profiles of ESRRB in both porcine pluripotent stem cells and...
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