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Article

An Oct4-centered protein interaction network in embryonic stem cells.

Cell stem cell - 2 Apr 2010

van den Berg Debbie L C, Snoek Tim, Mullin Nick P, Yates Adam, Bezstarosti Karel, Demmers Jeroen, Chambers Ian, Poot Raymond A

Abstract excerpt

Transcription factors, such as Oct4, are critical for establishing and maintaining pluripotent cell identity. Whereas the genomic locations of several pluripotency transcription factors have been reported, the spectrum of their interaction partners is underexplored. Here, we use an improved affinity protocol to purify Oct4-interacting proteins from mouse embryonic stem cells (ESCs). Subsequent purification of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20362541
DOI: 10.1016/j.stem.2010.02.014
PMCID: PMC2860243

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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