Back to search

Article

Cyp2b6 and Sult1a1 Single Nucleotide Polymorphism: Implication for Nevirapine-based Hiv Therapy Among Ghanaians

2023-05-18

Abstract excerpt

<h4>Background: </h4> Nevirapine is used in many developing countries for the management of HIV-1 patients. Despite its usefulness, hypersensitivity reaction is a common complication that accounts for patients defaulting during therapy in Ghana. Genetic variations in drug-metabolizing enzymes have been implicated in reported adverse drug reactions observed in patients on nevirapine regimen. The study determined ge...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
b5eff058-7bc4-57be-85ca-a7a5175f156a
DOI
10.21203/rs.3.rs-2650157/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Cyp2b6 and Sult1a1 Single Nucleotide Polymorphism: Implication for Nevirapine-based Hiv Therapy Among GhanaiansDOI 10.21203/rs.3.rs-2650157/v1
CYP2B6 c.983T>C polymorphism is associated with nevirapine hypersensitivity in Malawian and Ugandan HIV populations.Semantic proximity
Pharmacogenetics of CYP2B6, CYP2A6 and UGT2B7 in HIV treatment in African populations: focus on efavirenz and nevirapine.Semantic proximity
Role of pharmacogenetics and clinical parameters on nevirapine plasma concertation among HIV-1 patients receiving Antiretroviral Therapy in KenyaSemantic proximity
Prevalence of Cytochrome P450 2B6 Single Nucleotide Polymorphism in an HIV-Positive Cohort in Jos, Nigeria: Implication for HIV Therapy.Semantic proximity
CYP2B6 poor metaboliser alleles involved in efavirenz and nevirapine metabolism: CYP2B6*9 and CYP2B6*18 distribution in HIV-exposed subjects from Dschang, Western Cameroon.Semantic proximity
Toxicogenomics of nevirapine-associated cutaneous and hepatic adverse events among populations of African, Asian, and European descent.Semantic proximity
Allele and Genotype Frequencies of Cytochrome P450 2B6 516G>T Single Nucleotide Polymorphism in HIV-Negative and HIV-Infected Adult Nigerian Populations.Semantic proximity
Pharmacogenetic considerations for HIV treatment in different ethnicities: an update.Semantic proximity
The dual role of pharmacogenetics in HIV treatment: mutations and polymorphisms regulating antiretroviral drug resistance and disposition.Semantic proximity
Exploration of CYP450 and drug transporter genotypes and correlations with nevirapine exposure in Malawians.Semantic proximity
Nevirapine-induced hepatotoxicity and pharmacogenetics: a retrospective study in a population from Mozambique.Semantic proximity
Pharmacogenetics of nevirapine-associated hepatotoxicity: an Adult AIDS Clinical Trials Group collaboration.Semantic proximity
Select a neighboring publication to make it the new centre.