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Article

Exploration of CYP450 and drug transporter genotypes and correlations with nevirapine exposure in Malawians.

Pharmacogenomics - 1 Jan 2012

Brown Kevin C, Hosseinipour Mina C, Hoskins Janelle M, Thirumaran Ranjit K, Tien Hsiao-Chuan, Weigel Ralf, Tauzie Jean, Shumba Ida, Lamba Jatinder K, Schuetz Erin G, McLeod Howard L, Kashuba Angela D M, Corbett Amanda H

Abstract excerpt

AIM: Genetic polymorphisms have the potential to influence drug metabolism and vary among ethnic groups. This study evaluated the correlation of genetic polymorphisms with nevirapine pharmacokinetics exposure in Malawians. MATERIALS & METHODS: CYP450 2B6, 2D6, 3A4 and 3A5, ABCB1 and constitutive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22111602
DOI: 10.2217/pgs.11.132
PMCID: PMC3292264

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22111602-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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