Article
Pharmacogenetic considerations for HIV treatment in different ethnicities: an update.
Expert opinion on drug metabolism & toxicology - 1 Nov 2017
Neary M, Owen A
Abstract excerpt
INTRODUCTION: Variations in the human genome sequence sometimes play an important role in pharmacokinetics and/or pharmacodynamics. Previous studies have demonstrated a high degree of variation both between and within different ethnic populations. Areas covered: This review sought to summarize key SNPs in CYP2B6, CYP3A enzymes, CYP2C enzymes, UGT2 enzymes, ABCB1, ABCC2, SLCO1B1, NR1I2, and NR1I3 that have...
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