Article

Single cell analysis reveals the impact of age and maturation stage on the human oocyte transcriptome

2020-09-25

Abstract excerpt

<h4>Study question</h4> To which degree does maternal age affect the transcriptome of human oocytes at the germinal vesicle (GV) stage or at metaphase II after maturation in vitro (IVM-MII)? <h4>Summary answer</h4> While the oocytes’ transcriptome is predominantly determined by maturation stage, transcript levels of genes related to chromosome segregation, mitochondria and RNA processing are affected by age af...

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Literature Corpus work: b538b1ce-74ad-5d6e-9700-c8abfdf5397a
DOI: 10.1101/2020.09.25.309658

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