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The transcriptome of human oocytes is related to age and ovarian reserve

3 Jun 2017

Abstract excerpt

STUDY QUESTION: How does the human oocyte transcriptome change with age and ovarian reserve? SUMMARY ANSWER: Specific sets of human oocyte messenger RNAs (mRNAs) and non-coding RNAs (ncRNAs) are affected independently by age and ovarian reserve. WHAT IS KNOWN ALREADY: Although it is well established that the ovarian reserve diminishes with increasing age, and that a woman's age is correlated with lower oocyte...

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PMID: 28586423
DOI: 10.1093/molehr/gax033

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