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Transcriptomic analysis and epigenetic regulators in human oocytes at different stages of oocyte meiotic maturation

14 Dec 2024

Abstract excerpt

Human oocytes are highly specialized cells with the capacity to store and regulate mRNAs during oocyte maturation, in preparation for post-fertilization steps. Here we performed single-oocyte transcriptomic analysis of human oocytes in three meitoic maturation stages - Germinal Vesicle (GV; n = 6), Metaphase I (MI; n = 6) and Metaphase II (MII; n = 7). Single-oocyte transcriptomic analysis revealed that the total...

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PMID: 39681207
DOI: 10.1016/j.ydbio.2024.12.004

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