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Overview of Gene Expression Dynamics during Human Oogenesis/Folliculogenesis

19 Dec 2023

Abstract excerpt

The oocyte transcriptome follows a tightly controlled dynamic that leads the oocyte to grow and mature. This succession of distinct transcriptional states determines embryonic development prior to embryonic genome activation. However, these oocyte maternal mRNA regulatory events have yet to be decoded in humans. We reanalyzed human single-oocyte RNA-seq datasets previously published in the literature to decrypt...

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PMID: 38203203
DOI: 10.3390/ijms25010033

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