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Article

Aberrant spliceosome expression and altered alternative splicing events correlate with maturation deficiency in human oocytes

11 Aug 2020

Abstract excerpt

Different strategies of ovarian stimulation are widely used in IVF to retrieve mature metaphase II (MII) oocytes for fertilization. On average, approximately 70% of recovered oocytes are mature, while personalized administration of hCG and/or GnRH agonist trigger and in vitro maturation (IVM) management can further improve the maturation rate. However, even under such conditions, a complete absence of oocyte...

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PMID: 32779509
DOI: 10.1080/15384101.2020.1799295

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