Article

Microglia and macrophages alterations in the CNS during acute SIV infection: a single-cell analysis in rhesus macaques

2024-04-04

Abstract excerpt

<h4>ABSTRACT</h4> Human Immunodeficiency Virus (HIV) is widely acknowledged for its profound impact on the immune system. Although HIV primarily affects peripheral CD4 T cells, its influence on the central nervous system (CNS) cannot be overlooked. Within the brain, microglia and CNS-associated macrophages (CAMs) serve as the primary targets for HIV, as well as for the simian immunodeficiency virus (SIV) in nonhu...

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Literature Corpus work: 0d1b9c96-ebc3-585d-b535-34f83e714a74
DOI: 10.1101/2024.04.04.588047

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