Back to search

Article

Cardiolipin remodeling reflects mitochondrial reprogramming in clear cell renal cell carcinoma

2026-08-06

Abstract excerpt

<title>Abstract</title> <p>Cardiolipin (CL) is a mitochondria-specific phospholipid essential for maintaining mitochondrial structure and function; however, its role in clear cell renal cell carcinoma (ccRCC) remains unclear. We performed comprehensive phospholipidomic profiling using LC-TQMS on paired tumor and adjacent normal kidney tissues from ccRCC patients, complemented by immunoblotting, immunohistochemist...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
b4fbd268-77fc-5f51-93f7-56120bed457a
DOI
10.21203/rs.3.rs-9968356/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Cardiolipin remodeling reflects mitochondrial reprogramming in clear cell renal cell carcinomaDOI 10.21203/rs.3.rs-9968356/v1
MBOAT7-Driven Phosphatidylinositol Remodeling Promotes the Progression of Clear Cell Renal CarcinomaSemantic proximity
Lipid in Renal Carcinoma: Queen Bee to Target?Semantic proximity
VHL Mutation Drives Human Clear Cell Renal Cell Carcinoma Progression Through PI3K/AKT-Dependent Cholesteryl Ester AccumulationSemantic proximity
VHL mutation drives human clear cell renal cell carcinoma progression through PI3K/AKT-dependent cholesteryl ester accumulation.Semantic proximity
Early Lipid Remodeling During Ischemia–Reperfusion Injury Is Associated with Damage- and Protection-Related Lipid Signatures in Acute Kidney InjurySemantic proximity
Multi-omic profiling of clear cell renal cell carcinoma identifies metabolic reprogramming associated with disease progressionSemantic proximity
Barth syndrome cellular models have dysregulated respiratory chain complex I and mitochondrial quality control due to abnormal cardiolipinSemantic proximity
Cardiolipin Remodeling as a Regulatory Switch in Osteogenesis: Insights from Multimodal Metabolic Imaging and Molecular ProfilingSemantic proximity
System biology analysis reveals the role of voltage-dependent anion channel in mitochondrial dysfunction during non-alcoholic fatty liver disease progression into hepatocellular carcinoma.Semantic proximity
MTARC1 Regulates Lipid Droplet Degradation via Phospholipid Remodeling in Metabolic Fatty Liver DiseaseSemantic proximity
Abnormal oxidative metabolism in a quiet genomic background underlies clear cell papillary renal cell carcinomaSemantic proximity
Saturated cardiolipins are potent disruptors of inner mitochondrial membrane structure and functionSemantic proximity
Select a neighboring publication to make it the new centre.