Article

Cardiolipin Remodeling as a Regulatory Switch in Osteogenesis: Insights from Multimodal Metabolic Imaging and Molecular Profiling

2025-12-23

Abstract excerpt

<h4>ABSTRACT</h4> Cardiolipin (CL), a mitochondria-specific phospholipid, plays a fundamental role in respiratory chain organization and bioenergetic efficiency, yet its contribution to osteogenic differentiation is poorly defined. Here, we used a multimodal approach integrating untargeted LC–MS lipidomics, Raman spectroscopy, fluorescence lifetime imaging microscopy (FLIM), and structural imaging to investigate...

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Literature Corpus work: e1b3f213-9430-5c0c-89bd-31b1045e326a
DOI: 10.64898/2025.12.22.696122

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