Article
System biology analysis reveals the role of voltage-dependent anion channel in mitochondrial dysfunction during non-alcoholic fatty liver disease progression into hepatocellular carcinoma.
Cancer science - 1 Nov 2020
Zhu Yanping, Zhang Chao, Xu Fuyi, Zhao Miaoqing, Bergquist Jonas, Yang Chunhua, Liu Xiuxiu, Tan Ying, Wang Xiang, Li Shasha, Jiang Wenguo, Ong Qunxiang, Lu Lu, Mi Jia, Tian Geng
Abstract excerpt
Non-alcoholic fatty liver disease (NAFLD) is one of the most common causes of hepatocellular carcinoma (HCC), but the underlying mechanisms behind the correlation of NAFLD with HCC are unclear. We aimed to uncover the genes and potential mechanisms that drive this progression. This study uncovered the genes and potential mechanisms through a multiple 'omics integration approach. Quantitative proteomics combined...
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