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Early-onset schizophrenia is associated with immune-related rare variants in a Chinese sample

2023-11-22

Abstract excerpt

<h4>Background</h4> Rare variants are likely to contribute to schizophrenia (SCZ), given the large discrepancy between the heritability estimated from twin and GWAS studies. Furthermore, the nature of the rare-variant contribution to SCZ may vary with the “age-at-onset” (AAO), since early-onset has been suggested as being indicative of neurodevelopment deviance. <h4>Objective</h4> To examine the association of rar...

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Literature Corpus work
b4f1a771-b4f4-51d7-a170-5f2714c2aa92
DOI
10.1101/2023.11.21.23298115
Open publication

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Early-onset schizophrenia is associated with immune-related rare variants in a Chinese sampleDOI 10.1101/2023.11.21.23298115
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