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Novel genetic susceptibility loci identified by family based whole exome sequencing in Han Chinese schizophrenia patients.

Translational psychiatry - 16 Jan 2020

Li Mo, Shen Lu, Chen Luan, Huai Cong, Huang Hailiang, Wu Xi, Yang Chao, Ma Jingsong, Zhou Wei, Du Huihui, Fan Lingzi, He Lin, Wan Chunling, Qin Shengying

Abstract excerpt

Schizophrenia (SCZ) is a highly heritable psychiatric disorder that affects approximately 1% of population around the world. However, early relevant studies did not reach clear conclusions of the genetic mechanisms of SCZ, suggesting that additional susceptibility loci that exert significant influence on SCZ are yet to be revealed. So, in order to identify novel susceptibility genes that account for the genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32066673
DOI: 10.1038/s41398-020-0708-y
PMCID: PMC7026419

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