Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Whole-exome sequencing in a Chinese sample provides preliminary evidence for the link between rare/low-frequency immune-related variants and early-onset schizophrenia.

Asian journal of psychiatry - 1 Jun 2024

Zhong Yuanxin, Tubbs Justin D, Leung Perry B M, Zhan Na, Hui Tomy C K, Ho Karen K Y, Hung Karen S Y, Cheung Eric F C, So Hon-Cheong, Lui Simon S Y, Sham Pak C

Abstract excerpt

Rare and low-frequency variants contribute to schizophrenia (SCZ), and may influence its age-at-onset (AAO). We examined the association of rare or low-frequency deleterious coding variants in Chinese patients with SCZ. We collected DNA samples in 197 patients with SCZ spectrum disorder and 82 healthy controls (HC), and performed exome sequencing. The AAO variable was ascertained in the majority of SCZ...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Age of Onset

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to East Asian People

Share to Exome Sequencing

Share to Genetic Predisposition to Disease

Share to Schizophrenia

Share to Young Adult

Source

Identifiers

PMID: 38663229
DOI: 10.1016/j.ajp.2024.104046

Genes

PADI2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Whole-exome sequencing in a Chinese sample provides preliminary evidence for the link between rare/low-frequency immune-related variants and early-onset schizophrenia.PMID 38663229Read ↗

Early-onset schizophrenia is associated with immune-related rare variants in a Chinese sampleSemantic proximity Read ↗

Genome wide association study identifies four loci for early onset schizophrenia.Semantic proximity Read ↗

Novel genetic susceptibility loci identified by family based whole exome sequencing in Han Chinese schizophrenia patients.Semantic proximity Read ↗

Exome sequencing in families with severe mental illness identifies novel and rare variants in genes implicated in Mendelian neuropsychiatric syndromesSemantic proximity Read ↗

Identifying novel proteins underlying schizophrenia via integrating pQTLs of the plasma, CSF, and brain with GWAS summary dataSemantic proximity Read ↗

Biological Insights from Schizophrenia-associated Loci in Ancestral PopulationsSemantic proximity Read ↗

Common genetic variants contribute to heritability of age at onset of schizophreniaSemantic proximity Read ↗

Epigenome-Wide Association Studies in Cases and Controls With High and Low Genetic Risk for SchizophreniaSemantic proximity Read ↗

Rare schizophrenia risk variant burden is conserved in diverse human populationsSemantic proximity Read ↗

Exome sequencing in 53 sporadic cases of schizophrenia identifies 18 putative candidate genes.Semantic proximity Read ↗

Gene-level analysis reveals the genetic aetiology and therapeutic targets of schizophrenia.Semantic proximity Read ↗

Exome sequencing in families with severe mental illness identifies novel and rare variants in genes implicated in Mendelian neuropsychiatric syndromesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.