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Genome wide association study identifies four loci for early onset schizophrenia.

Translational psychiatry - 27 Apr 2021

Guo Suqin, Liu Jiewei, Li Wenqiang, Yang Yongfeng, Lv Luxian, Xiao Xiao, Li Ming, Guan Fanglin, Luo Xiong-Jian

Abstract excerpt

Early onset schizophrenia (EOS, defined as first onset of schizophrenia before age 18) is a rare form of schizophrenia (SCZ). Though genome-wide association studies (GWASs) have identified multiple risk variants for SCZ, most of the cases included in these GWASs were not stratified according to their first age at onset. To date, the genetic architecture of EOS remains largely unknown. To identify the risk...

Topics

Adolescent
Case-Control Studies
Genetic Loci
Genetic Predisposition to Disease
Genome-Wide Association Study
Humans
Polymorphism, Single Nucleotide
Schizophrenia

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33907183
DOI: 10.1038/s41398-021-01360-4
PMCID: PMC8079394

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