Article

Common genetic variants contribute to heritability of age at onset of schizophrenia

2023-01-23

Abstract excerpt

<title>Abstract</title><p>Schizophrenia (SCZ) is a complex disorder that typically arises in late adolescence or early adulthood. Age at onset (AAO) of SCZ is associated with long-term outcomes of the disease. We explored the genetic architecture of AAO with a genome-wide association study (GWAS), heritability, polygenic risk score (PRS), and copy number variant (CNV) analyses in 4 740 subjects of European ancestr...

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Literature Corpus work: e380a314-2cbe-572c-afd7-ed4bf4a6a4f6
DOI: 10.21203/rs.3.rs-2487478/v1

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