Article
High resolution human leukocyte antigen class I allele frequencies and HIV-1 infection associations in Chinese Han and Uyghur cohorts.
PloS one - 1 Jan 2012
Liu Yanhou, Zhao Zhongfang, Li Tianyi, Liao Qi, Kushner Nicholas, Touzjian Neal Y, Shao Yiming, Sun Yongtao, Strong Amie J, Lu Yichen
Abstract excerpt
BACKGROUND: Host immunogenetic factors such as HLA class I polymorphism are important to HIV-1 infection risk and AIDS progression. Previous studies using high-resolution HLA class I profile data of Chinese populations appeared insufficient to provide information for HIV-1 vaccine development and clinical trial design. Here we reported HLA class I association with HIV-1 susceptibility in a Chinese Han and a...
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