Article
Structural studies of spliceosome assembly and catalysis
2019-01-01
Abstract excerpt
Eukaryotic genes contain non-coding introns, removal of which during gene expression is a pre-requisite for gene function. Removal of introns and ligation of coding exons --a process called splicing--is catalysed by a dynamic macromolecular machine called the spliceosome. The spliceosome assembles anew on precursor mRNA (pre-mRNA) from its component small nuclear ribonucleoproteins (snRNPs) and protein factors. A...
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Identifiers and source
- Literature Corpus work
- b42f7d6f-b392-51e1-8f02-ca244dd5fd19
- DOI
- 10.17863/cam.42226