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Article

SnapShot: Spliceosome Dynamics III.

Cell - 30 Jul 2015

Wahl Markus C, Lührmann Reinhard

Abstract excerpt

The complex compositional and conformational dynamics of spliceosomes required for regulated splicing are prone to malfunction when mutations affect splicing factors or cis-acting regulatory sequences. Indeed, many such mutations have been linked to heritable diseases or malignancies in humans. Small molecule modulators and antisense oligonucleotides or analogs harbor great potential for therapies and several...

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Identifiers

PMID: 26232231
DOI: 10.1016/j.cell.2015.07.033

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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