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Article

Mechanisms and Regulation of Alternative Pre-mRNA Splicing.

Annual review of biochemistry - 1 Jan 2015

Lee Yeon, Rio Donald C

Abstract excerpt

Precursor messenger RNA (pre-mRNA) splicing is a critical step in the posttranscriptional regulation of gene expression, providing significant expansion of the functional proteome of eukaryotic organisms with limited gene numbers. Split eukaryotic genes contain intervening sequences or introns disrupting protein-coding exons, and intron removal occurs by repeated assembly of a large and highly dynamic...

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Identifiers

PMID: 25784052
DOI: 10.1146/annurev-biochem-060614-034316
PMCID: PMC4526142

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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