Article

PGLYRP-1 mediated intracellular peptidoglycan detection promotes mucosal protection

2024-10-14

Abstract excerpt

<title>Abstract</title> <p>Peptidoglycan recognition proteins (PGRPs or PGLYRPs) are implicated in the control of the intestinal microbiota; however, molecular requirements for peptidoglycan (PGN) binding and receptor signaling mechanisms remain poorly understood. We identified PGLYRP-1 as a receptor for the disaccharide motif of lysine N-acetylglucosamine N-acetylmuramic tripeptide (GMTriP-K) with a newly constr...

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Literature Corpus work: b3d81c89-0ebe-555e-880d-63f62b6b2a38
DOI: 10.21203/rs.3.rs-5118704/v1

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